Nature Mental Health, Published online: 18 September 2026; doi:10.1038/s44220-026-00729-y
Major depressive disorder (MDD) remains challenging to treat effectively due to limited understanding of its neural mechanisms. Here the authors use machine learning to analyze early functional connectivity changes in patients with MDD who are receiving medication, revealing distinct neural circuits associated with antidepressant and placebo responses, which could enhance personalized treatment strategies.
via Nature Mental Health https://ift.tt/x8mv5d2

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